Reaktion #2395448

Reaktionsgleichung

3,5-bis(4-hydroxyphenyl)-4-methylthiophene-2-carbaldehyde

methoxylamine hydrochloride

→

title compound

Ausbeute 62.1%

3,5-Bis(4-hydroxyphenyl)-4-methylthiophene-2-carbaldehyde O-methyloxime

Ausbeute 62.1%

Reaktionsbedingungen

Vorschrift

Starting from 3,5-bis(4-hydroxyphenyl)-4-methylthiophene-2-carbaldehyde (0.86 g, 2.8 mmol) in place of 3-(3-methoxyphenyl)-5-(4-methoxyphenyl)-4-methylthiophene-2-carbaldehyde and methoxylamine hydrochloride (0.25 g, 3.0 mmol) in place of hydroxylamine hydrochloride, the title compound (0.59 g, 62%, m.p. 219-25° C.) was synthesized in essentially the same manner as described in Example 16, Step 1. Contains 6% E form as determined by NOE.

Quelle