Reaktion #2395435

Reaktionsgleichung

2-[3-bromo-5-(4-methoxyphenyl)-4-methylthien-2-yl]-1,3-dioxolane

2-[3-Bromo-5-(4-methoxyphenyl)-4-methylthien-2-yl]-1,3-dioxolane

5-methoxy-2-methylphenylboronic acid

→

title compound

Ausbeute 89.0%

3-(5-Hydroxy-2-methylphenyl)-5-(4-hydroxyphenyl)-4-methyl-2-thiophenecarbaldehyde

Ausbeute 89.0%

Reaktionsbedingungen

Vorschrift

Starting from 2-[3-bromo-5-(4-methoxyphenyl)-4-methylthien-2-yl]-1,3-dioxolane (1.1 g, 3.0 mmol, made in Example 1, Step 1) and substituting 5-methoxy-2-methylphenylboronic acid (0.55 g, 3.3 mmol) in place of 3-methoxyphenylboronic acid (Step 2), the title compound (0.49 g, 89%, m.p. 204-07° C.) was synthesized in essentially the same manner as described in Example 1, Steps 2-4.

Quelle