Reaktion #2395433

Reaktionsgleichung

2-(3-bromo-5-iodo-4-methylthien-2-yl)-1,3-dioxolane

3-methoxyphenylboronic acid

4-methoxyphenylboronic acid

→

title compound

Ausbeute 85.0%

3-(3-Hydroxyphenyl)-5-(4-hydroxyphenyl)-4-methylthiophene-2-carbaldehyde

Ausbeute 85.0%

Reaktionsbedingungen

Vorschrift

Starting from 2-(3-bromo-5-iodo-4-methylthien-2-yl)-1,3-dioxolane (9.3 g, 25 mmol) and substituting 3-methoxyphenylboronic acid (4.1 g, 27 mmol) in place of 4-methoxyphenylboronic acid (Example 1, Step 1) and substituting 4-methoxyphenylboronic acid in place of 3-methoxyphenylboronic acid (Example 1, Step 2), the title compound (0.40 g, 85%, m.p. 208-10° C.) was synthesized in essentially the same manner as described in Example 1.

Quelle