Reaktion #2394490

Reaktionsgleichung

N-(4-chlorobenzyl)-2-(chloromethyl)-3,7-dimethyl-4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamide

2-(hydroxy(phenyl)methyl)pyrrolidine

→

title compound

N-(4-Chlorobenzyl)-2-(((2R*)-2-((S*)-hydroxy(phenyl)methyl)pyrrolidin-1-yl)-methyl)-3,7-dimethyl-4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamide

Reaktionsbedingungen

Vorschrift

Analogous to the procedures described in Example 2, N-(4-chlorobenzyl)-2-(chloromethyl)-3,7-dimethyl-4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamide (Preparation 30) is treated with 2-(hydroxy(phenyl)methyl)pyrrolidine (Preparations 2) to afford the title compound.

Quelle