Reaktion #2383007

Reaktionsgleichung

6-dibenzylamino-3,5-dimethylbenzofuran-2(3H)-one

hydrogen

→

6-amino-3,5-dimethylbenzofuran-2(3H)-one

Lösungsmittel

dioxane

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe mixture is then filtered
2. 2
   Einengenthe filtrate is concentrated to dryness by evaporation
3. 3
   Sonstigerecrystallised from methanol

Vorschrift

4 g of 6-dibenzylamino-3,5-dimethylbenzofuran-2(3H)-one are dissolved in 40 ml of dioxane and reduction is carried out at room temperature, under normal pressure, with hydrogen and with 0.4 g of palladium-on-carbon. The mixture is then filtered, and the filtrate is concentrated to dryness by evaporation and recrystallised from methanol. In this manner 6-amino-3,5-dimethylbenzofuran-2(3H)-one having a melting point of 123°-124° C. is obtained.

Quelle