Reaktion #2366313

Reaktionsgleichung

4-[4-(8,8-Dimethyl-6,9-diaza-spiro[4.5]dec-9-ylmethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-6-yl]-3-fluoro-phenol

3-Fluoro-4-{3-methyl-4-[2,2,5,5-tetramethyl-4-(3,3,3-trifluoro-propyl)-piperazin-1-ylmethyl]-1H-pyrazolo[3,4-b]pyridin-6-yl}-phenol

formaldehyde

→

title compound

3-Fluoro-4-[3-methyl-4-(6,8,8-trimethyl-6,9-diaza-spiro[4.5]dec-9-ylmethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-phenol

Reaktionsbedingungen

Vorschrift

The title compound was prepared in analogy to Example 65 (3-Fluoro-4-{3-methyl-4-[2,2,5,5-tetramethyl-4-(3,3,3-trifluoro-propyl)-piperazin-1-ylmethyl]-1H-pyrazolo[3,4-b]pyridin-6-yl}-phenol) using 4-[4-(8,8-Dimethyl-6,9-diaza-spiro[4.5]dec-9-ylmethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-6-yl]-3-fluoro-phenol and aqueous formaldehyde.

Quelle