Reaktion #2363607

Reaktionsgleichung

methyl-5-amino-3-(3-fluorophenyl)isoxazol-4-carboxylate

sodium hydroxide

→

required compound

Ausbeute 55.0%

5-amino-3-(3-fluorophenyl)isoxazol-4-carboxylic acid

Ausbeute 55.0%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeIn a similar manner as described in Preparation Example 25

Vorschrift

In a similar manner as described in Preparation Example 25, by using methanol (60 mL), methyl-5-amino-3-(3-fluorophenyl)isoxazol-4-carboxylate (6.0 g, 25.40 mmol) and 3% sodium hydroxide aqueous solution (60 mL), a white solid required compound (3.08 g, 13.86 mmol, 55%) was obtained.

Quelle