Reaktion #2358454

Reaktionsgleichung

ethyl 2-methyl-3,4,6-trifluorobenzoylacetate

acetic anhydride

ethyl orthoformate

→

ethyl 2-(2-methyl-3,4,6-trifluorobenzoyl)-3-ethoxyacrylate

Ausbeute 90.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturby heating
2. 2
   Temperaturrefluxing for 1 hour
3. 3
   EinengenThe resulting mixture was concentrated

Vorschrift

To 3.2 g of ethyl 2-methyl-3,4,6-trifluorobenzoylacetate were added 3.0 g of acetic anhydride and 2.7 g of ethyl orthoformate, followed by heating and refluxing for 1 hour. The resulting mixture was concentrated to give 3.5 g of ethyl 2-(2-methyl-3,4,6-trifluorobenzoyl)-3-ethoxyacrylate.

Quelle