Reaktion #2355331

Reaktionsgleichung

triethyloxonium tetrafluoroborate

( 9.0.0 )

1-Cyclopentyl-3-ethyl-1,4,5,6-tetrahydropyrazolo[3,4-c]pyridin-7-one

triethyloxonium tetrafluoroborate

( 9.0.0 )

1-Cyclopentyl-3-ethyl-1,4,5,6-tetrahydropyrazolo[3,4-c]pyridin-7-one

→

( 10.0.0 )

1-Cyclopentyl-7-ethoxy-3-ethyl-4,5-dihydro-1H-pyrazolo[3,4-c]pyridine

Lösungsmittel

methylene chloride

methylene chloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturand thereafter, maintaining
2. 2
   Sonstigereaction mixture at a temperature of from 18° to 22° C.

Vorschrift

esterifying said lactam compound of Formula (9.0.0) using triethyloxonium tetrafluoroborate, (CH3CH2)2OBF4; wherein a reaction mixture is established by slowly adding a solution of triethyloxonium tetrafluoroborate, (CH3CH2)3OBF4 in methylene chloride to a suspension of said lactam compound of Formula (9.0.0) in methylene chloride over a period of 40 minutes; and thereafter, maintaining said reaction mixture at a temperature of from 18° to 22° C., for a period of 21 hours; whereby there is produced a corresponding imino ester (imidate) compound of Formula (10.0.0):

Quelle