Reaktion #2354764

Reaktionsgleichung

5-(phenyl)-3-(4-piperidinyl)-1H-indole-7-carboxamide

5-chloro-1,3-dimethyl-1H-pyrazole-4-sulfonyl chloride

triethylamine

TEA

→

desired product

3-{1-[(5-chloro-1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl]-4-piperidinyl}-5-phenyl-1H-indole-7-carboxamide

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigewere reacted

Vorschrift

Following the general procedure in example 267, 5-(phenyl)-3-(4-piperidinyl)-1H-indole-7-carboxamide (32 mg, 0.1 mmol), 5-chloro-1,3-dimethyl-1H-pyrazole-4-sulfonyl chloride (34.5 mg, 0.15 mmol) and triethylamine (0.06 mL, 0.3 mmol) were reacted to form the desired product which was purified by Gilson HPLC (CH3CN/Water, 0.1% TFA) (22 mg, 43%).

Quelle