Reaktion #2350537

Reaktionsgleichung

2-oxo-2-phenylethyl thiocyanate

water

sulfuric acid

→

desired product

Ausbeute 84.3%

4-Phenyl-1,3-thiazol-2-ol

Ausbeute 84.3%

Lösungsmittel

acetic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationA formed precipitate was collected by filtration
2. 2
   Waschenwashed with water

Vorschrift

A mixed solution of 2-oxo-2-phenylethyl thiocyanate (5.67 g, 32.0 mmol), water (3.2 ml), concentrated sulfuric acid (0.832 ml) and acetic acid (26 ml) was stirred at 130° C. for 2 hours and at room temperature for 2 hours. A formed precipitate was collected by filtration and washed with water to give 4.78 g (84.3%) of the desired product.

Quelle