Reaktion #2347252

Reaktionsgleichung

16-hexadecanolide

methanol

→

methyl 16-hydroxyhexadecanoate

Ausbeute 90.2%

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe reaction mixture was cooled
2. 2
   FiltrationThe crystals were collected by filtration
3. 3
   Waschenwashed
4. 4
   Sonstigedried

Vorschrift

76.3 gm of 16-hexadecanolide and 0.29 gm of 28% sodium methoxide solution were dissolved into 250 gm of methanol, and the solution was heated at 60° C. for 60 hours while stirring. The reaction mixture was cooled to deposit crystals. The crystals were collected by filtration, washed, and dried to obtain 77.5 gm of methyl 16-hydroxyhexadecanoate (yield: 90.2%).

Quelle