Reaktion #2346938

Reaktionsgleichung

acetic acid

5-(2-benzyloxyethyl)-6-methyl-1,3-benzodioxole

→

intended compound

Ausbeute 79.0%

2-(6-Methyl-1,3-benzodioxol-5-yl)ethanol

Ausbeute 79.0%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeAfter removing palladium/carbon, ethanol
2. 2
   workup.DISTILLATIONwas distilled off
3. 3
   Sonstigethe product was purified

Vorschrift

1.9 g of 5-(2-benzyloxyethyl)-6-methyl-1,3-benzodioxole was dissolved in 80 ml of ethanol. 0.2 g of 10% palladium/carbon (containing 50% water) and 4 ml of acetic acid was added thereto and the catalytic reduction was conducted under 3 atm/cm2 for 1 h. After removing palladium/carbon, ethanol was distilled off and the product was purified according to silica gel column chromatography (ethyl acetate/hexane=2:3) to obtain 1.0 g of the intended compound in the form of a faint yellow oil.

Quelle