Reaktion #2336533

Reaktionsgleichung

2-Methylthiophenol

potassium carbonate

DMF

→

title compound

Ausbeute 42.0%

3,6-Bis(2′-methylphenylthio) phthalonitrile

Ausbeute 42.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe mixture was isolated
2. 2
   Sonstigeto give a yellow oil
3. 3
   SonstigeThe material was purified by flash column chromatography (eluting 10% ethyl acetate:isohexane)

Vorschrift

2-Methylthiophenol (10.60 g, 85.5 mmol), potassium carbonate (11.82 g, 82.0 mmol) and ditosylated dicyanohydroquinone (20.00 g, 42.7 mmol) in DMF (75 mL) were reacted as described above. The mixture was isolated as described above to give a yellow oil. The material was purified by flash column chromatography (eluting 10% ethyl acetate:isohexane) to give the title compound as a yellow solid (8.85 g, 23.8 mmol, 42%). [Found: C, 70.7%; H, 4.6%; N, 7.5%; S, 17.2%; C22H16N2S2 requires C, 70.9%; H, 4.3%; N, 7.5%; S, 17.2%]; MS (EI+) 372 (M+, 100%), 357 (M-CH3, 8), 339 (20).

Quelle