Reaktion #2335558

Reaktionsgleichung

5-acetyl-6-hydroxy-4,7-dimethoxybenzofuran

→

desired product

Ausbeute 96.2%

5-acetyl-2,3-dihydro-6-hydroxy-4,7-dimethoxybenzofuran

Ausbeute 96.2%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeat room temperature
2. 2
   SonstigeWhen the absorption of hydrogen
3. 3
   Filtrationthe mixture is filtered
4. 4
   workup.DISTILLATIONthe solvent is distilled off

Vorschrift

10 g of 5-acetyl-6-hydroxy-4,7-dimethoxybenzofuran in 100 ml of methanol are hydrogenated using 2 g of Pd/C (10%) at room temperature and under slightly superatmospheric pressure. When the absorption of hydrogen is complete, the mixture is filtered and the solvent is distilled off. 9.7 g of the desired product of melting point 100°-101° C. are obtained.

Quelle