Reaktion #2335047

Reaktionsgleichung

2-cyano-5-formylthiophene

benzoylmethylenetriphenylphosphorane

→

3-(5-cyano-2-thienyl)-1-phenyl-2-propen-1-one

Ausbeute 56.6%

Lösungsmittel

tetrahydrofuran

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas refluxed for 30 minutes
2. 2
   SonstigeThe reaction mixture was evaporated in vacuo

Vorschrift

A mixture of 2-cyano-5-formylthiophene (4 g) and benzoylmethylenetriphenylphosphorane (11.09 g) in tetrahydrofuran (40 ml) was refluxed for 30 minutes. The reaction mixture was evaporated in vacuo to give 3-(5-cyano-2-thienyl)-1-phenyl-2-propen-1-one (3.95 g).

Quelle