Reaktion #2333216

ord-f7e0ec7850974fed9a3c39de22141308

Reaktionsgleichung

C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12
androstenedione
C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CCC2=O
estrone
→
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C=O)[C@@H]1CCC2=O
19-Aldoandrostenedione

Edukte

C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12
androstenedione
C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CCC2=O
estrone

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

This compound is the postulated reaction intermediate of the second hydroxylation step of androstenedione-to-estrone catalysis by Aromatase.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07687252B2uspto-grants-2010_03