Reaktion #2320104

ord-3e3e36bfa43f4b0691fec661b4d2f193

Reaktionsgleichung

Clc1ccc(Br)cc1Cl
4-bromo-1,2-dichlorobenzene
CCCN1[C@H](C)CNC[C@@H]1C
cis-2,6-dimethyl-1-propyl-piperazine
Cl
HCl
→
CCCN1[C@H](C)CN(c2ccc(Cl)c(Cl)c2)C[C@@H]1C
cis-4-(3,4-dichloro-phenyl)-2,6-dimethyl-1-propyl-piperazine

Edukte

—
( 64 )
—
( 53 )
Clc1ccc(Br)cc1Cl
4-bromo-1,2-dichlorobenzene
CCCN1[C@H](C)CNC[C@@H]1C
cis-2,6-dimethyl-1-propyl-piperazine
—
( 47 )
Cl
HCl

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigethe title compound was recovered by the procedure
  2. 2
    Sonstigedescribed in Preparation 9

Vorschrift

Beginning with 4-bromo-1,2-dichlorobenzene and cis-2,6-dimethyl-1-propyl-piperazine, the title compound was recovered by the procedure described in Preparation 9: m.p. 225° C. (HCl), MS m/z (rel. intensity, 70 eV)) 301 (M+, 24), 271 (64), 112 (bp), 70 (47), 56 (53).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: USRE041315E1uspto-grants-2010_05