Reaktion #2314279

Reaktionsgleichung

bromopentane

→

2-Pentyl-1,3-butadiene

Lösungsmittel

ammonium chloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturgradually warming to room temperature
2. 2
   workup.STIRRINGThe reaction mixture is stirred for 10 minutes, during which time the aqueous layer
3. 3
   ExtraktionThe reaction mixture is then extracted with hexanes
4. 4
   Trocknenthe combined organic layers are dried over magnesium sulfate
5. 5
   SonstigeThe solvent is carefully removed by rotary evaporation
6. 6
   Sonstigeto give 17 g of a colorless, malodorous liquid

Vorschrift

To a flask containing cuprous bromide (1.0 g) is added bromopentane (23 g) and tetrahydrofaran (154 mL). The solution is cooled to 0° C., and the Grignard reagent 1B is added. The reaction is stirred overnight, gradually warming to room temperature. To the solution is then added 30 mL saturated ammonium chloride. The reaction mixture is stirred for 10 minutes, during which time the aqueous layer turns blue. The reaction mixture is then extracted with hexanes, and the combined organic layers are dried over magnesium sulfate. The solvent is carefully removed by rotary evaporation to give 17 g of a colorless, malodorous liquid.

Quelle