Reaktion #2298623

Reaktionsgleichung

(7-bromothieno[3,2-d]pyrimidin-4-yl)hydrazine hydrochloride

(7-Bromothieno[3,2-d]pyrimidin-4-yl)hydrazine hydrochloride

3-pyridinecarboxaldehyde

→

3-pyridinecarboxaldehyde(7-bromothieno[3,2-d]pyrimidin-4-yl)hydrazone

Ausbeute 81.0%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas heated
2. 2
   Temperaturat reflux for 4 hours
3. 3
   Filtrationthe solid product was collected by vacuum filtration

Vorschrift

A suspension of (7-bromothieno[3,2-d]pyrimidin-4-yl)hydrazine hydrochloride (168, 29 mg, 0.12 mmol) and 3-pyridinecarboxaldehyde (18 mg, 0.17 mmol) in ethanol (2 mL) was heated at reflux for 4 hours. After cooling to room temperature, the solid product was collected by vacuum filtration to yield 3-pyridinecarboxaldehyde(7-bromothieno[3,2-d]pyrimidin-4-yl)hydrazone (32 mg, 81% yield) as a pale yellow solid.

Quelle