Reaktion #2230

Reaktionsgleichung

water

4-(bromomethyl)benzonitrile

sodium hydride

imidazolin-2-one

→

4,4'-[(2-oxoimidazolin-1,3-diyl) bis(methylene)]-bis(benzonitrile)

Lösungsmittel

dimethylformamide

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONwas added
2. 2
   Sonstigea solid formed
3. 3
   FiltrationThe solid was filtered

Vorschrift

To sodium hydride (2.4 g, 60 mmol) in dimethylformamide (50 mL) at 0° C. was added imidazolin-2-one (2.6 g, 30 mmol). After stirring for 20 minutes 4-(bromomethyl)benzonitrile (13 g, 66 mmol) was added and the mixture was warmed to ambient temperature. After stirring for 1 hour the reaction was poured into water and a solid formed. The solid was filtered to give 4,4'-[(2-oxoimidazolin-1,3-diyl) bis(methylene)]-bis(benzonitrile). NMR (CDCl3) 7.65 (d,4), 7.4 (d,4), 4.45 (s,4), 3.2 (s,4) ppm.

Quelle