Reaktion #220773

Reaktionsgleichung

1-(tert-Butoxycarbonyl)-4-[[N-(9-fluorenylmethyloxycarbonyl)glycyl]aminomethyl]piperidine

HCl

→

4-[[N-(9-fluorenylmethyloxycarbonyl)glycyl]aminomethyl]piperidine

Ausbeute 152.4%

Lösungsmittel

dioxane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Einengenconcentrated

Vorschrift

1-(tert-Butoxycarbonyl)-4-[[N-(9-fluorenylmethyloxycarbonyl)glycyl]aminomethyl]piperidine (3.17 g, 6.42 mmol) was added to a 4 M dioxane solution of HCl. The resulting solution was stirred at room temperature for 5 hours and concentrated to afford 4-[[N-(9-fluorenylmethyloxycarbonyl)glycyl]aminomethyl]piperidine (3.85 g) as an off-white solid. The obtained product was used without further purification.

Quelle