Reaktion #220558

ord-8ed8181bf0e04a71ae3a25e77b78e5f2

Reaktionsgleichung

O=C(O)Cc1cccs1
2-thiopheneacetic acid
CCC(N)C(=O)OCC(C)C
iso-butyl 2-aminobutyrate
→
CCC(NC(=O)Cc1cccs1)C(=O)OCC(C)C
title compound
CCC(NC(=O)Cc1cccs1)C(=O)OCC(C)C
2-[(2-thienyl)acetamido]butyric acid iso-butyl ester

Edukte

O=C(O)Cc1cccs1
2-thiopheneacetic acid
CCC(N)C(=O)OCC(C)C
iso-butyl 2-aminobutyrate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe reaction was monitored by dc on silica gel and purification
  2. 2
    Filtrationwas by filtration

Vorschrift

Following General Procedure BI above and using 2-thiopheneacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by dc on silica gel and purification was by filtration as described in the general procedure.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07390801B2uspto-grants-2008_06