Reaktion #220545

ord-1bd48728b09d40e7b0e6df233bde8924

Reaktionsgleichung

O=C(O)Cc1ccc([N+](=O)[O-])cc1
4-nitrophenylacetic acid
CCC(N)C(=O)OCC(C)C
iso-butyl 2-aminobutyrate
→
CCC(NC(=O)Cc1ccc([N+](=O)[O-])cc1)C(=O)OCC(C)C
title compound
CCC(NC(=O)Cc1ccc([N+](=O)[O-])cc1)C(=O)OCC(C)C
2-[(4-nitrophenyl)acetamido]butyric acid iso-butyl ester

Edukte

O=C(O)Cc1ccc([N+](=O)[O-])cc1
4-nitrophenylacetic acid
CCC(N)C(=O)OCC(C)C
iso-butyl 2-aminobutyrate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe reaction was monitored by tlc on silica gel and purification
  2. 2
    Filtrationwas by filtration

Vorschrift

Following General Procedure BI above and using 4-nitrophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07390801B2uspto-grants-2008_06