Reaktion #2204729

Reaktionsgleichung

{3-[(4-pyrazol-1-yl-benzylamino)-methyl]-phenoxy}-acetic acid tert-butyl ester

pyridine-2-sulfonyl chloride hydrochloride

→

title compound

(3-{[(4-Pyrazol-1-yl-benzyl)-(pyridine-2-sulfonyl)-amino]-methyl}-phenoxy)-acetic acid tert-butyl ester

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigedescribed in Example 3, Step B with a reaction time of 2 h

Vorschrift

The title compound of Step A was prepared from {3-[(4-pyrazol-1-yl-benzylamino)-methyl]-phenoxy}-acetic acid tert-butyl ester, of Step A of Example 13a, and pyridine-2-sulfonyl chloride hydrochloride, of Preparation 47, following the method described in Example 3, Step B with a reaction time of 2 h. 1H NMR (400 MHz, CDCl3) δ8.66 (m, 1H), 7.95 (d, 1H), 7.85 (m, 2H), 7.68 (d, 1H), 7.49 (d, 2H), 7.45 (m, 1H), 7.16 (d, 2H), 7.08 (t, IH), 6.70 (m, 3H), 6.43 (m, 1H), 4.49 (s, 2H), 4.44 (s, 2H), 4.38 (s, 2H), 1.46 (s, 9H); MS 535 (M+1).

Quelle