Reaktion #220444
ord-130745f3862e46b4a7d3cb95f03b50b4
Reaktionsgleichung
1,3-Dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
isobutyl iodide
→
1,3-dihydro-1-isobutyl-5-phenyl-2H-1,4-benzodiazepin-2-one
Reagenzien
Keine
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
1,3-Dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one (prepared according to the procedure of M. G. Bock et al., J. Org. Chem. 1987, 52, 3232-3239) was alkylated with isobutyl iodide using General Procedure 8-G to afford 1,3-dihydro-1-isobutyl-5-phenyl-2H-1,4-benzodiazepin-2-one.