Reaktion #220379

ord-e11367379dd64b83acc0b01f108af7d9

Reaktionsgleichung

O=C(O)CC1CCCC1
cyclopentylacetic acid
COC(=O)[C@H](C)N.Cl
L-alanine methyl ester hydrochloride
→
COC(=O)[C@H](C)NC(=O)CC1CCCC1
title compound
COC(=O)[C@H](C)NC(=O)CC1CCCC1
N-(Cyclopentylacetyl)-L-alanine Methyl Ester

Edukte

O=C(O)CC1CCCC1
cyclopentylacetic acid
COC(=O)[C@H](C)N.Cl
L-alanine methyl ester hydrochloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigePurification
  2. 2
    Sonstigewas by recrystallization from ethyl acetate/hexanes

Vorschrift

Following General Procedure A above using cyclopentylacetic acid (Aldrich) and L-alanine methyl ester hydrochloride (Sigma), the title compound was prepared as a solid having a melting point of 43-46° C. Purification was by recrystallization from ethyl acetate/hexanes.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07390801B2uspto-grants-2008_06