Reaktion #220366

Reaktionsgleichung

6-chloropiperonyl alcohol

PBr3

→

powder

5-Bromomethyl-6-chloro-1,3-benzodioxole

Lösungsmittel

ethyl ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONIt is poured onto ice
2. 2
   Extraktionextraction
3. 3
   WaschenThe organic phase is washed with a saturated NaCl solution

Vorschrift

2.5 g of 6-chloropiperonyl alcohol are dissolved in 80 ml of ethyl ether. The solution is cooled to 0° C. and then 1.9 ml of PBr3 are added. The mixture is stirred at ambient temperature for 18 hours. It is poured onto ice and then extraction is carried out with AcOEt. The organic phase is washed with a saturated NaCl solution. 3.3 g of powder are obtained.

Quelle