Reaktion #220365

Reaktionsgleichung

3-bromophenylacetic acid

ethanol

H2SO4

→

expected compound

Ethyl 3-bromophenylacetate

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe mixture is heated
2. 2
   Temperaturat reflux for two hours
3. 3
   SonstigeThe ethanol is evaporated
4. 4
   Extraktionextraction
5. 5
   TrocknenThe organic phase is dried over MgSO4

Vorschrift

5 g of 3-bromophenylacetic acid are dissolved in 80 ml of ethanol, 3 ml of concentrated H2SO4 are added and then the mixture is heated at reflux for two hours. The ethanol is evaporated, neutralization is carried out with a saturated K2CO3 solution and then extraction is carried out with AcOEt. The organic phase is dried over MgSO4. 5.2 g of the expected compound are obtained in the liquid form.

Quelle