Reaktion #220256

Reaktionsgleichung

mesitylenesulfonyl chloride

N-pyrazin-2-ylcyclopropanecarboxamide

O-mesitylenesulfonylhydroxylamine

→

title compound

1-Amino-2-[(cyclopropylcarbonyl)amino]pyrazin-1-ium 2,4,6-trimethylbenzenesulfonate

Lösungsmittel

dichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   EinengenThe resultant thick yellow mixture was concentrated in vacuo

Vorschrift

To a solution of 1.0 g (6.13 mmol) of N-pyrazin-2-ylcyclopropanecarboxamide in 10 mL of dichloromethane at 0° C. was added a solution of 1.58 g (7.36 mmol) of O-mesitylenesulfonylhydroxylamine, prepared from mesitylenesulfonyl chloride using a procedure analogous to that described in the literature (Y. Tamura et al., J. Org. Chem., 38: 1239 (1973)). The reaction mixture was allowed to stir at ambient temperature for 1.5 h. The resultant thick yellow mixture was concentrated in vacuo to give the title compound as a yellow solid.

Quelle