Reaktion #2200590
ord-7a3e402a4a8b4604936da49f3e7c46ea
Reaktionsgleichung
indolepyruvic acid
pyruvic acid
oxalacetic acid
→
4-(indol-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid
Reagenzien
Keine
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
According to the study by the present inventors, it has been found that PtALD can catalyze the aldol condensation reaction of indolepyruvic acid with pyruvic acid (or oxalacetic acid) to yield 4-(indol-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid (IHOG), and the reaction of phenylpyruvic acid with pyruvic acid to yield 4-phenylmethyl-4-hydroxy-2-oxoglutaric acid (PHOG).