Reaktion #2191887

ord-e36cdb9f0b86480d8a42101349c73388

Reaktionsgleichung

Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1
{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amine
COc1ccc(C=O)c(OC)c1OC
2,3,4-trimethoxybenzaldehyde
→
COc1ccc(CNc2cccc(-c3c(Cc4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c(OC)c1OC
title compound
COc1ccc(CNc2cccc(-c3c(Cc4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c(OC)c1OC
{3-[3-BENZYL-8-(TRIFLUOROMETHYL)QUINOLIN-4-YL]PHENYL}(2,3,4-TRIMETHOXYBENZYL)AMINE

Edukte

Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1
{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amine
COc1ccc(C=O)c(OC)c1OC
2,3,4-trimethoxybenzaldehyde

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from {3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amine and 2,3,4-trimethoxybenzaldehyde to the procedure of step 1, Example 66. MS (ESI) m/z 559.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07576215B2uspto-grants-2009_08