Reaktion #218282

Reaktionsgleichung

phenothiazine

acetyl chloride

→

beige solid

10-acetyl-10H-phenothiazine

Lösungsmittel

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONare added to a 500 ml flask
2. 2
   EinengenAfter concentration to dryness
3. 3
   Filtrationfiltered
4. 4
   SonstigeAfter drying

Vorschrift

20 g (0.1 mol) of phenothiazine followed by 14.3 ml (2 eq.) of acetyl chloride are added to a 500 ml flask containing 200 ml of toluene. The heterogeneous reaction mixture is stirred for 1 hour at 50° C. After concentration to dryness, the precipitate is taken up in a minimum of isopentane and filtered. After drying, 24 g of a beige solid is obtained with a quantitative yield. Melting point: 210-211° C.

Quelle