Reaktion #2170812

Reaktionsgleichung

4-nitro-1-cyclohexyl-1H-benzotriazole

Hydrogen

→

4-amino-1-cyclohexyl-1H-benzotriazole

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstige2 hours
2. 2
   Sonstigethe catalyst is then removed by filtration
3. 3
   SonstigeOn evaporation of the solvent
4. 4
   Sonstigethe product is isolated in quantitative yield as an oil, which

Vorschrift

In a 500 ml. Paar hydrogenator is placed 49.2 g. of the 4-nitro-1-cyclohexyl-1H-benzotriazole, 220 ml. ethanol and 2.5 g. 10% palladium on carbon catalyst and the mixture is heated to 45° C. Hydrogen is introduced at about 40 psi and the temperature of the reaction is maintained at 60° C. The reaction is over after 11/2 hours and the catalyst is then removed by filtration. On evaporation of the solvent, the product is isolated in quantitative yield as an oil, which solidifies on standing, m.p. 54°-60° C. Analysis Calcd. for C12H16N4 : C, 66.64; H, 7.46; N, 25.90. Found: C, 66.38; H, 7.55; N, 25.69.

Quelle