Reaktion #216909

Reaktionsgleichung

di-2-pyridyl ketone

L-cysteine

→

2,2-di(2-pyridyl)-thiazolidine-4-carboxylic acid

Ausbeute 11.0%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas refluxed for 3.5 hours
2. 2
   Temperaturto cool
3. 3
   Filtrationthe insoluble matter was filtered off
4. 4
   Einengenthe filtrate was concentrated to dryness under reduced pressure
5. 5
   WaschenThe residue was washed in sequence with ethyl acetate and ether

Vorschrift

A mixture of 3.68 g of di-2-pyridyl ketone, 2.42 g of L-cysteine, 25 ml of ethanol was refluxed for 3.5 hours. After allowing the mixture to cool, the insoluble matter was filtered off, and the filtrate was concentrated to dryness under reduced pressure. The residue was washed in sequence with ethyl acetate and ether to give 0.63 g of 2,2-di(2-pyridyl)-thiazolidine-4-carboxylic acid.

Quelle