Reaktion #2161296

Reaktionsgleichung

para-methoxy benzyl azide

propionic acid ethyl ester-

→

crude title compound

Ausbeute 95.0%

ethyl 1-(4-methoxybenzyl)-1H-1,2,3-triazole-4-carboxylate

Ausbeute 95.0%

Lösungsmittel

DMF

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONAfter the addition
2. 2
   SonstigeThe mixture was evaporated in vacuo

Vorschrift

To a solution of para-methoxy benzyl azide (125.0 g, 0.77 mol) in anhydrous DMF (300 mL) was added dropwise propionic acid ethyl ester-(166 g, 1.77 mol) at 0° C. After the addition, the mixture was stirred at RT overnight. The mixture was evaporated in vacuo to yield crude title compound (190.0 g, 95.0%) as yellow oil that was used without further purification.

Quelle