Reaktion #216078

Reaktionsgleichung

laurylamine

glycidol

→

3-Laurylamino-1,2-Dihydroxy-Propane

Ausbeute 59.0%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe methanol was then removed by rotary evaporation
2. 2
   SonstigeAfter recrystallization from hexane, LDP
3. 3
   Sonstigewas recovered as a white crystal, m.p. 75°-76° C. (m.p. 76°-76.5° C., lit.)

Vorschrift

The procedures of Ulsperger et al., J. Prakt. Chemie, Vol. 27, pp. 195-212 (1965), the disclosures of which are hereby incorporated herein by reference in their entirety, were substantially followed. Specifically, 18.54 g laurylamine (0.1M) and 7.4 g glycidol (0.1M) were mixed in 150 ml methanol at 60° C. for 5 hours. The mixture was refluxed for 1 hour at 70° C. The methanol was then removed by rotary evaporation. The product was a solid, 15.3 g (59% yield). After recrystallization from hexane, LDP, was recovered as a white crystal, m.p. 75°-76° C. (m.p. 76°-76.5° C., lit.).

Quelle