Reaktion #215931

Reaktionsgleichung

4-Cyanophenyl hydrazine hydrochloride

sodium acetate

4-Phthalimido cyclohexanone

→

3-phthalimido-6-cyano-1,2,3,4-tetrahydrocarbazole

Lösungsmittel

acetic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe mixture heated
2. 2
   Temperaturunder reflux overnight
3. 3
   SonstigeThe solvent was removed in vacuo
4. 4
   Sonstigethe residue triturated with methanol

Vorschrift

4-Cyanophenyl hydrazine hydrochloride (4.41 g, 0.026 mole) was dissolved in acetic acid (100 ml) and sodium acetate (2 g) was added. 4-Phthalimido cyclohexanone (6.4 g, 0.026 mole) was added and the mixture heated under reflux overnight. The solvent was removed in vacuo and the residue triturated with methanol to give 3-phthalimido-6-cyano-1,2,3,4-tetrahydrocarbazole as a beige solid, (5.3 g).

Quelle