Reaktion #215875

Reaktionsgleichung

N-[cyclopropyl(4-pyridyl)methyl]-N-propylthiourea

Compound 74

N-[cyclopropyl(4-pyridyl)methyl]-N-propylthiourea

2-bromo-1-(2,4-dichlorophenyl)-1-propanone

→

4-(2,4-dichlorophenyl)-5-methyl-2-{N-[cyclopropyl(4-pyridyl)methyl]-N-propylamino}thiazole

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThis compound was prepared
2. 2
   SonstigeThe product was purified on a silica column
3. 3
   workup.ADDITIONa mixture of methylene chloride and methanol (98:2 V/V) as eluent

Vorschrift

This compound was prepared according to the process described in Example 1, starting with 1.2 g of N-[cyclopropyl(4-pyridyl)methyl]-N-propylthiourea (Compound 74) and 1.52 g of 2-bromo-1-(2,4-dichlorophenyl)-1-propanone Compound 15). The product was purified on a silica column, using a mixture of methylene chloride and methanol (98:2 V/V) as eluent.

Quelle