Reaktion #215708

Reaktionsgleichung

ethyl 2-(2,5-dichloro-3,4,6-trifluorobenzoyl)-3-ethoxyacrylate

cyclopropylamine

→

Ethyl 2-(2,5-dichloro-3,4,6-trifluorobenzoyl)-3-cyclopropylaminoacrylate

Lösungsmittel

ethanol

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONare added dropwise
2. 2
   FiltrationThe precipitate is filtered off with suction
3. 3
   Waschenwashed with petroleum ether
4. 4
   Sonstigedried in air

Vorschrift

37.1 g (0.1 mol) of ethyl 2-(2,5-dichloro-3,4,6-trifluorobenzoyl)-3-ethoxyacrylate are initially introduced into the reaction vessel in 100 ml of ethanol. 6.8 g (0.12 mol) of cyclopropylamine, dissolved in 10 ml of ethanol, are added dropwise. The mixture is then stirred at room temperature for 4 hours. The precipitate is filtered off with suction, washed with petroleum ether and dried in air.

Quelle