Reaktion #215574

Reaktionsgleichung

2,3-Dicyano-5-chloro-6-(m-bromophenyl)pyrazine

ethylamine

→

2,3-dicyano-5-ethylamino-6-(m-bromophenyl)pyrazine

Ausbeute 80.0%

Lösungsmittel

tetrahydrofuran

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigerecrystallized from ethanol

Vorschrift

2,3-Dicyano-5-chloro-6-(m-bromophenyl)pyrazine (1.15 g; 0.0036 mole) was dissolved in 20 ml of tetrahydrofuran. The solution was cooled to 0° C., and 0.50 g of a 70% aqueous solution of ethylamine was added. The mixture was worked up in the same way as in Example 13, and recrystallized from ethanol to afford 0.95 g (yield 80%) of 2,3-dicyano-5-ethylamino-6-(m-bromophenyl)pyrazine.

Quelle