Reaktion #215570

Reaktionsgleichung

2,3-Dicyano-5-chloro-6-isobutylpyrazine

n-propylamine

sodium hydroxide

→

2,3-dicyano-5-n-propylamino-6-isobutylpyrazine

Ausbeute 85.5%

Lösungsmittel

tetrahydrofuran

Reaktionsbedingungen

Vorschrift

2,3-Dicyano-5-chloro-6-isobutylpyrazine (1.10 g; 0.005 mole) was dissolved in 20 ml of tetrahydrofuran. The solution was worked up in the same way as in Example 13 using 0.30 g (0.005 mole) of n-propylamine and 0.02 g (0.005 mole) of sodium hydroxide to afford 1.04 g (yield 85%) of 2,3-dicyano-5-n-propylamino-6-isobutylpyrazine.

Quelle