Reaktion #215569

Reaktionsgleichung

2,3-Dicyano-5-chloro-6-n-butylpyrazine

methylamine

→

2,3-dicyano-5-methylamino-6-n-butylpyrazine

Ausbeute 81.0%

Lösungsmittel

benzene

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.STIRRINGThen, the mixture was stirred at 30° to 40° C. for 2 hours

Vorschrift

2,3-Dicyano-5-chloro-6-n-butylpyrazine (2.21 g; 0.01 mole) was dissolved in 30 ml of benzene, and with stirring at 30° C., 1.55 g (0.02 mole) of a 40% aqueous solution of methylamine was added. Then, the mixture was stirred at 30° to 40° C. for 2 hours. The reaction mixture was worked up in the same way as in Example 13 to afford 1.75 g (yield 81%) of 2,3-dicyano-5-methylamino-6-n-butylpyrazine.

Quelle