Reaktion #215468

ord-1e200182c410436d83b80e49fe290b98

Reaktionsgleichung

COC(=O)C1=C(O)c2sc3cc(C)ccc3c2S(=O)(=O)N1C
methyl 2,7-dimethyl-4-hydroxy-2H-[1]-benzothieno-[2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide
Nc1ncccc1O
2-amino-3-hydroxy-pyridine
→
Cc1ccc2c3c(sc2c1)C(O)=C(C(=O)Nc1ncccc1O)N(C)S3(=O)=O
2,7-Dimethyl-4-hydroxy-N-(3-hydroxy-2pyridyl)-2H-[1]-benzothieno-[2,3-e]-1,2-thiazine-3-carboxamide-1,1-dioxide
Ausbeute 38.0%

Edukte

COC(=O)C1=C(O)c2sc3cc(C)ccc3c2S(=O)(=O)N1C
methyl 2,7-dimethyl-4-hydroxy-2H-[1]-benzothieno-[2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide
Nc1ncccc1O
2-amino-3-hydroxy-pyridine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepared analogous to Example 1 from methyl 2,7-dimethyl-4-hydroxy-2H-[1]-benzothieno-[2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide and 2-amino-3-hydroxy-pyridine with a yield of 38% of theory.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04259336uspto-grants-1981_03