Reaktion #2154653

Reaktionsgleichung

4-(trifluoromethyl)benzyl bromide

4-(bromomethyl)-5-phenyloxazole

ethyl 4-methyl-2-(2-oxoimidazolidin-1-yl)thiazole-5-carboxylate

→

title compound

Ausbeute 81.0%

ethyl 4-methyl-2-(2-oxo-3-((5-phenyloxazol-4-yl)methyl)imidazolidin-1-yl)thiazole-5-carboxylate

Ausbeute 81.0%

Reaktionsbedingungen

Vorschrift

Following the procedure as described in Example 13, making variations as required to replace 4-(trifluoromethyl)benzyl bromide with 4-(bromomethyl)-5-phenyloxazole to react with ethyl 4-methyl-2-(2-oxoimidazolidin-1-yl)thiazole-5-carboxylate, the title compound was obtained as a colorless solid in 81% yield: MS (ES+) m/z 413.1 (M+1).

Quelle