Reaktion #215414

Reaktionsgleichung

2-butylamino-4-methyloxazole

allyl isocyanate

→

1-Allyl-3-butyl-3-(4-methyl-2-oxazolyl)urea

Lösungsmittel

benzene

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturunder reflux for 4 hours
2. 2
   SonstigeThe product was further purified by chromatography on a silica-gel column
3. 3
   Wascheneluting with a 1:1 mixture of benzene and ethyl acetate

Vorschrift

A solution of 2-butylamino-4-methyloxazole (12.0 g, 0.078 mol) and allyl isocyanate (6.46 g, 0.078 mol) in dry benzene was heated under reflux for 4 hours, and worked up as described in Example 3. The product was further purified by chromatography on a silica-gel column, eluting with a 1:1 mixture of benzene and ethyl acetate.

Quelle