Reaktion #215412

Reaktionsgleichung

2-butylamino-4-methyloxazole

ethyl isocyanate

→

1-Butyl-3-ethyl-1-(4-methyl-2-oxazolyl)urea

Lösungsmittel

benzene

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturunder reflux for 2 hours
2. 2
   Sonstigeevaporated to dryness
3. 3
   workup.DISSOLUTIONThe residual oil was dissolved in ether
4. 4
   Waschenthe solution was washed with 2 N HCl
5. 5
   Sonstigedried
6. 6
   Sonstigeevaporated
7. 7
   workup.DISTILLATIONThe residue was distilled under vacuum b.p. 128° C./1.0 mm

Vorschrift

A solution of 2-butylamino-4-methyloxazole (15.0 g, 0.0972 mol) and ethyl isocyanate (7.6 g, 0.107 mol) in dry benzene was heated under reflux for 2 hours and then evaporated to dryness. The residual oil was dissolved in ether and the solution was washed with 2 N HCl, dried and evaporated. The residue was distilled under vacuum b.p. 128° C./1.0 mm. IR 3275, 1696, 1590 cm-1.

Quelle