Reaktion #215390

Reaktionsgleichung

product

N,N-di[(2-hydroxy)ethyl]taurine

3,4,5-trimethoxybenzoyl chloride

→

N,N-di-[2-(3,4,5-trimethoxybenzoyloxy)ethyl]taurine

Lösungsmittel

ethanol

pyridine

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturIt was then cooled to ambient temperature
2. 2
   workup.WAITleft
3. 3
   SonstigeA colourless crystalline compound precipitated which
4. 4
   Sonstigemilted at 174°-178° C
5. 5
   SonstigeAfter recrystallisation from methanol

Vorschrift

8.5 G of the product obtained in Example 2 (a) was suspended in 25 ml of anhydrous pyridine, and 18.4 g of 3,4,5-trimethoxybenzoyl chloride added slowly under agitation. After being left for one hour at ambient temperature the mixture was heated to 80° C. for a further hour. It was then cooled to ambient temperature, diluted with 50 ml of ethanol and left to stand in a refrigerator. A colourless crystalline compound precipitated which milted at 174°-178° C. After recrystallisation from methanol, the melting point was 180°-183° C. The yield was 11.5 g of pure product.

Quelle