Reaktion #2152014

ord-894bcb70ca1a494a914c75068e4c0299

Reaktionsgleichung

Cc1nc2sccn2c1C(=O)NC[C@@H]1C[C@@H]2C[C@@H]2N1
6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide
O=C(O)c1ccccc1-n1cccn1
2-pyrazol-1-yl-benzoic acid
→
Cc1nc2sccn2c1C(=O)NC[C@@H]1C[C@@H]2C[C@@H]2N1C(=O)c1ccccc1-n1cccn1
6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1S,3S,5S)-2-(2-pyrazol-1-yl-benzoyl)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide

Edukte

Cc1nc2sccn2c1C(=O)NC[C@@H]1C[C@@H]2C[C@@H]2N1
6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide
O=C(O)c1ccccc1-n1cccn1
2-pyrazol-1-yl-benzoic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

prepared by reaction of 6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide with 2-pyrazol-1-yl-benzoic acid. LC-MS (basic): tR=1.19 min; [M+H]+=447.1.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08288435B2uspto-grants-2012_10