Reaktion #2152

ord-02b576534acf4dda8bd059063a4bc1e5

Reaktionsgleichung

CCn1cnc2c1c(=O)[nH]c(=O)n2C
7-ethyl-3-methylxanthine
CP(C)(=O)CCl
chloromethyl-dimethylphosphine oxide
→
CCn1cnc2c1c(=O)n(CP(C)(C)=O)c(=O)n2C
[1-(7-Ethyl-3-methylxanthin-1-yl)methyl]dimethylphosphine Oxide

Edukte

CCn1cnc2c1c(=O)[nH]c(=O)n2C
7-ethyl-3-methylxanthine
CP(C)(=O)CCl
chloromethyl-dimethylphosphine oxide

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title substance was prepared from 5 g (0.0258 mol) of 7-ethyl-3-methylxanthine and 3.91 g (0.031 mol) of chloromethyl-dimethylphosphine oxide analogously to Example 67.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05728686uspto-grants-1998_03